The bestselling author of Leonardo da Vinci and Steve Jobs returns with a gripping account of how Nobel Prize winner Jennifer Doudna and her colleagues launched a revolution that will allow us to cure diseases, fend off viruses, and have healthier babies. When Jennifer Doudna was in sixth grade, she came home one day to find that her dad had left a paperback titled The Double Helix on her bed. She put it aside, thinking it was one of those detective tales she loved. When she read it on a rainy Saturday, she discovered she was right, in a way. As she sped through the pages, she became enthralled by the intense drama behind the competition to discover the code of life. Even though her high school counselor told her girls didn’t become scientists, she decided she would. Driven by a passion to understand how nature works and to turn discoveries into inventions, she would help to make what the book’s author, James Watson, told her was the most important biological advance since his co-discovery of the structure of DNA. She and her collaborators turned ​a curiosity ​of nature into an invention that will transform the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions. The development of CRISPR and the race to create vaccines for coronavirus will hasten our transition to the next great innovation revolution. The past half-century has been a digital age, based on the microchip, computer, and internet. Now we are entering a life-science revolution. Children who study digital coding will be joined by those who study genetic code. Should we use our new evolution-hacking powers to make us less susceptible to viruses? What a wonderful boon that would be! And what about preventing depression? Hmmm…Should we allow parents, if they can afford it, to enhance the height or muscles or IQ of their kids? After helping to discover CRISPR, Doudna became a leader in wrestling with these moral issues and, with her collaborator Emmanuelle Charpentier, won the Nobel Prize in 2020. Her story is a thrilling detective tale that involves the most profound wonders of nature, from the origins of life to the future of our species.

Presents a portrait of Benjamin Franklin as a scientist, inventor, diplomat, writer, business strategist, and statesman while tracing his life as one of America’s Founding Fathers.

NOW A MAJOR SERIES ‘GENIUS’ ON NATIONAL GEOGRAPHIC, PRODUCED BY RON HOWARD AND STARRING GEOFFREY RUSH Einstein is the great icon of our age: the kindly refugee from oppression whose wild halo of hair, twinkling eyes, engaging humanity and extraordinary brilliance made his face a symbol and his name a synonym for genius. He was a rebel and nonconformist from boyhood days. His character, creativity and imagination were related, and they drove both his life and his science. In this marvellously clear and accessible narrative, Walter Isaacson explains how his mind worked and the mysteries of the universe that he discovered. Einstein’s success came from questioning conventional wisdom and marvelling at mysteries that struck others as mundane. This led him to embrace a worldview based on respect for free spirits and free individuals. All of which helped make Einstein into a rebel but with a reverence for the harmony of nature, one with just the right blend of imagination and wisdom to transform our understanding of the universe. This new biography, the first since all of Einstein’s papers have become available, is the fullest picture yet of one of the key figures of the twentieth century. This is the first full biography of Albert Einstein since all of his papers have become available — a fully realised portrait of this extraordinary human being, and great genius. Praise for EINSTEIN by Walter Isaacson:- ‘YOU REALLY MUST READ THIS.’ Sunday Times ‘As pithy as Einstein himself.’ New Scientist ‘[A] brilliant biography, rich with newly available archival material.’ Literary Review ‘Beautifully written, it renders the physics understandable.’ Sunday Telegraph ‘Isaacson is excellent at explaining the science. ‘ Daily Express

“He was history’s most creative genius. What secrets can he teach us? The [bestselling biographer] brings Leonardo da Vinci to life in this exciting new biography. Drawing on thousands of pages from Leonardo’s astonishing notebooks and new discoveries about his life and work, Walter Isaacson weaves a narrative that connects his art to his science. He shows how Leonardo’s genius was based on skills we can improve in ourselves, such as passionate curiosity, careful observation, and an imagination so playful that it flirted with fantasy. His creativity, like that of other great innovators, came from standing at the intersection of the humanities and technology. He peeled flesh off the faces of cadavers, drew the muscles that move the lips, and then painted history’s most memorable smile on the Mona Lisa. He explored the math of optics, showed how light rays strike the cornea, and produced illusions of changing perspectives in The Last Supper. Isaacson also describes how Leonardo’s lifelong enthusiasm for staging theatrical productions informed his paintings and inventions. His ability to combine art and science, made iconic by his drawing of what may be himself inside a circle and a square, remains the enduring recipe for innovation. His life should remind us of the importance of instilling, both in ourselves and our children, not just received knowledge but a willingness to question it; to be imaginative and, like talented misfits and rebels in any era, to think different.”–Jacket.

Draws on more than forty interviews with Steve Jobs, as well as interviews with family members, friends, competitors, and colleagues to offer a look at the co-founder and leading creative force behind the Apple computer company.

A revelatory history of the people who created the computer and the internet discusses the process through which innovation happens in the modern world, citing the pivotal contributions of such figures as programming pioneer Ada Lovelace. By the author of Steve Jobs. 500,000 first printing.

A captivating blend of personal biography and public drama, The Wise Men introduces the original best and brightest, leaders whose outsized personalities and actions brought order to postwar chaos: Averell Harriman, the freewheeling diplomat and Roosevelt’s special envoy to Churchill and Stalin; Dean Acheson, the secretary of state who was more responsible for the Truman Doctrine than Truman and for the Marshall Plan than General Marshall; George Kennan, self-cast outsider and intellectual darling of the Washington elite; Robert Lovett, assistant secretary of war, undersecretary of state, and secretary of defense throughout the formative years of the Cold War; John McCloy, one of the nation’s most influential private citizens; and Charles Bohlen, adroit diplomat and ambassador to the Soviet Union.

In this collection of essays, the brilliant, acclaimed biographer Walter Isaacson reflects on lessons to be learned from Benjamin Franklin, Albert Einstein, Bill Gates, Henry Kissinger, Ronald Reagan and Mikhail Gorbachev, Hillary Clinton and Bill Clinton, and other interesting characters he has chronicled both as biographer and journalist. He writes also about how he became a writer, the challenges for journalism in the digital age, and offers loving tributes to his hometown of New Orleans.

This exclusive boxed set from beloved New York Times bestselling author Walter Isaacson features his definitive biographies: Steve Jobs, Einstein, Benjamin Franklin, and Leonardo da Vinci. “If anybody in America understands genius, it’s Walter Isaacson.” —Salon Celebrated historian, journalist, and bestselling author Walter Isaacson’s biography collection of geniuses now available in one boxed set—the perfect gift for history lovers everywhere. Steve Jobs: The “enthralling” (The New Yorker) worldwide bestselling biography of legendary Apple cofounder Steve Jobs. The story of the roller-coaster life and intense creative entrepreneur whose passion for perfection and ferocious drive revolutionized six industries: personal computers, animated movies, music, phones, tablet computing, and digital publishing. Isaacson’s portrait touched millions of readers. Einstein: How did his mind work? What made him a genius? Isaacson’s biography of Albert Einstein—also the basis for the ten-part National Geographic series starring Geoffrey Rush—shows how Einstein’s scientific imagination sprang from the rebellious nature of his personality. His fascinating story is a testament to the connection between creativity and freedom. Benjamin Franklin: In this colorful and intimate narrative, Isaacson provides the full sweep of Ben Franklin’s amazing life, showing how the most fascinating Founding Father helped forge the American national identity. Leonardo da Vinci: History’s consummate innovator and most creative thinker. Isaacson illustrates how Leonardo’s genius was based on skills we can improve in ourselves, such as passionate curiosity, careful observation, and an imagination so playful that it flirted with fantasy.